Researchers Identify Gene Associated with Cancer

March 1, 2012

Cells with too few or too many chromosomes have long been known
to be a hallmark of cancer—but the cause of this abnormal number
of chromosomes has been little understood. Now researchers at
Georgetown Lombardi have identified a gene that is commonly mutated in
human cancers and have demonstrated its direct role in causing aneuploidy, an
abnormal number of chromosomes. MD/PhD student David Solomon and
his mentor, cancer geneticist Todd Waldman, MD, PhD, were among the
team that made the discovery.