Fisher Center Pilot Grants Awarded to 2 Lombardi Faculty Members

April 30, 2010

The Fisher Center for Familial Cancer Research awarded its annual pilot grants to two Lombardi faculty members.Mitchell Jung, PhD, and Peter Shields, MD, were the 2010 recipients of the $20,000 one-year awards.

Each year, the Fisher Center awards two grants to fund novel basic science, clinical, epidemiological or behavioral research projects that directly support the mission of the Fisher Center. The intention of the grants is to provide funding for new projects by faculty members, post-doctoral students and junior researchers to obtain preliminary results and go on to compete for national funding. The awards are reviewed by the directors of the Fisher Center, and ad-hoc faculty, as needed. Members of the Fisher Center and Georgetown University faculty are eligible to apply.

Jung, an assistant professor of Biochemistry and Molecular Biology, will be studying the role of PARP-1 on DNA damage response and repair. One goal of this research is to determine the ADP-ribose-associated DNA repair factors in normal and BRCA mutatant cells. Shields, who is deputy director of Lombardi and professor of medicine and oncology, will be conducting a study on metablomic profiling of women after oophorectomy, which may ultimately provide important information for women as they make informed decisions about undergoing this procedure. For example, the findings may shed light on why women experience different degrees of menopausal symptoms after this procedure.

The Fisher Center seeks to advance the understanding of familial cancer by calling on the expertise of scientists in basic science, epidemiology, and cancer prevention. The Center’s mission is to conduct state-of-the-art research on the prevention, treatment and management of familial cancers in order to improve the medical and quality of life outcomes of men and women at risk of cancer.

Author: Nkem T. Wellington